Work
Selected research, software, and teaching resources. Projects are grouped by the clinical or methodological question they address, with papers, code, and supporting materials linked together.
Browse the complete publication list, or explore research on Hypercapnic Respiratory Failure and Respiratory Measurement.
Hypercapnic respiratory failure and respiratory measurement
The Consistency of Hypercapnic Respiratory Failure Case Definitions in Electronic Health Record Data
A comparison of reproducible EHR definitions for identifying hypercapnic respiratory failure.
doi:10.1016/j.chest.2025.08.002 PubMed Repository: Hypercapnic Respiratory Failure Case Definitions
Emergency Department Presenting Concerns Among Admissions With Hypercapnia: A Retrospective NLP Study of MIMIC-IV
A MIMIC-IV study using natural language processing to characterize presenting concerns among admissions with hypercapnia.
doi:10.64898/2026.07.03.26357242 Repository: Hypercapnia Presenting-Concern NLP Study
The association of weight loss from anti-obesity medications or bariatric surgery and apnea-hypopnea index in obstructive sleep apnea
A systematic review and meta-regression relating weight loss to change in sleep-apnea severity.
doi:10.1111/obr.13697 PubMed Repository: Weight Loss and OSA Meta-analysis
Use of High-Dose Hydroxocobalamin for Septic Shock
Surgical and N95 Masks in Chronic Hypercapnic Respiratory Failure: What Physiology Can and Cannot Tell Us
An editorial interpreting the physiologic and symptom effects of surgical and N95 masks in chronic hypercapnic respiratory failure.
The Role of Obstructive Sleep Apnea in Hypercapnic Respiratory Failure Identified in Critical Care, Inpatient, and Outpatient Settings
OSA and Chronic Respiratory Disease: Mechanisms and Epidemiology
Severity, comorbidities, and adherence to therapy in Native Hawaiians/Pacific Islanders with obstructive sleep apnea
doi:10.5664/jcsm.10472 Repository: Native Hawaiian and Pacific Islander OSA Burden
What Are We Aiming for in Chronic Hypercapnic Respiratory Failure?
Electronic health record–derived outcomes in obstructive sleep apnea managed with positive airway pressure tracking systems
doi:10.5664/jcsm.9750 Repository: Electronic Health Record-derived CPAP Outcomes
A55-47 Prognostic Value of Hypercapnia by ABG vs VBG: A Propensity-Weighted, Multicenter EHR Cohort
doi:10.1093/ajrccm/aamag162.4637 Repository: ABG versus VBG Project
C75-09 Chief Complaint Profiles in Hypercapnic Respiratory Failure: A Natural Language Processing Study of MIMIC-IV
doi:10.1093/ajrccm/aamag162.4737 Repository: Hypercapnia Presenting-Concern NLP Study
Simulation suggests transcutaneous CO2 sensors may accurately detect hypercapnia across settings
In silico evaluation of transcutaneous CO2 measurement performance for detecting hypercapnia.
Repository: Transcutaneous CO2 Accuracy Live tool: Transcutaneous CO2 Accuracy
In silico estimation of transcutaneous CO2 sensor performance
Repository: Transcutaneous CO2 Accuracy Live tool: Transcutaneous CO2 Accuracy
Hypercapnic respiratory failure is infrequently reported as an adverse event in clinical trials
Determinants of serum bicarbonate performance for identifying hypercapnia
Post-hospitalization care and health-services research
Exploring the Impact of Virtual Reality Interventions on Autonomic Arousal in ICU Patients
Post-Acute Ventilator Weaning and Discharge Outcomes in Individuals With Cervical Spinal Cord Injury
A retrospective cohort analysis of ventilator weaning and discharge outcomes after cervical spinal cord injury.
doi:10.1177/19433654261428406 PubMed Repository: Post-Acute Ventilator Weaning and Discharge Outcomes in Cervical Spinal Cord Injury
Immersive Virtual Reality Use in Medical Intensive Care: Mixed Methods Feasibility Study
A mixed-methods evaluation of immersive virtual reality among medical intensive-care patients.
doi:10.2196/62842 Repository: Immersive Virtual Reality in the ICU
Uncomfortable Truths About Data, Justice, and Idiopathic Pulmonary Fibrosis in the Veterans Health Administration
Mountain Medical Kits: Epidemiology-Based Recommendations and Analysis of Medical Supplies Carried by Mountain Climbers in Colorado
C58-05 Epidemiology of Sarcoidosis in Utah: Incidence, Organ Involvement, and Mortality Compared With National Benchmarks
C75-05 Costs Surrounding Index Hospitalization for Any-Cause Hypercapnic Respiratory Failure in an Integrated Healthsystem
Rates of diagnostic evaluation for causes of hypercapnic respiratory failure in Utah
Low research-burden study of immersive virtual reality feasibility in ICU
Journal article: Immersive Virtual Reality Use in Medical Intensive Care: Mixed Methods Feasibility Study Repository: Immersive Virtual Reality in the ICU
Diagnostic evidence, prediction, and research informatics
The information in diagnostic tests
A preprint examining the information in diagnostic tests, with separately cited registered protocol and supporting data and analysis code.
doi:10.64898/2026.09.13.26362573 Protocol: The information in diagnostic tests: registered protocol Dataset: The information in diagnostic tests: supporting data and analysis code
Meaning of clinical calculator results: a cross-sectional analysis of the MDCalc catalogue
Large language models generate diagnostic likelihood ratios with low mean bias but wide dispersion
doi:10.1038/s41598-026-61766-2 PubMed Repository: LLM Estimation of Likelihood Ratios
Splenectomy Increases CTEPH Risk and Modifies Clinical Features of Acute Pulmonary Embolism
doi:10.1002/pul2.70231 PubMed Repository: Splenectomy and Pulmonary Embolism
Diagnostic Modeling to Identify Unrecognized Inpatient Hypercapnia Using Health Record Data
A health-record model for identifying inpatient hypercapnia that may otherwise go unrecognized.
Decision Curve Analysis for Evaluating Machine Learning Models for Next-Day Transfer Out of ICU
A decision-curve analysis evaluating when ICU transfer prediction models could support next-day clinical workflows.
Entropy removal of clinical features
doi:10.1038/s41598-025-29069-0 PubMed Repository: Diagnostic Chat Entropy
Assessing Foundation Models' Transferability to Physiological Signals in Precision Medicine
Seeing the random forest for the Zzz's: machine learning's new role in sleep science
Hickam's Dictum: An Analysis of Multiple Diagnoses
The association between pulmonary artery enlargement and mortality in an Emergency Department population undergoing computed tomography pulmonary angiography
doi:10.1002/pul2.12225 Repository: Pulmonary Artery Enlargement and Mortality
The Verity of a Unifying Diagnosis
Central versus peripheral location of pulmonary embolism in asplenic patients
Decomposing treatment effect estimation reveals asymmetric clinical knowledge in large language models: analysis code, frozen prompts and aggregate results
Analysis code, frozen prompts, and aggregate results for treatment-effect estimation. This record is a dataset, not a manuscript publication.
Methods, software, and reproducible workflows
Parallel Circulation Oxygen Explorer
An interactive educational and research exploration of parallel circulation and oxygen transport. No formal release version is claimed; source-replication caveats remain documented in the repository.
Repository: Parallel Circulation Oxygen Explorer Live tool: Parallel Circulation Oxygen Explorer
VBG Acid–Base Explorer
A research and educational acid–base explorer. The version and date follow the source citation file; do not enter patient information or use it for clinical decisions.
Repository: VBG Acid–Base Explorer Live tool: VBG Acid–Base Explorer
Wald inference tools
An umbrella project for Wald inference tools, including confidence-curve and likelihood visualizations.
Repository: Wald inference tools Live tool: Wald inference tools Repository: Confidence Curves and Likelihood Live tool: Confidence Curves and Likelihood
MIMIC-CXR Bilateral Opacity Benchmark
An automated silver-label benchmark for bilateral opacity in MIMIC-CXR reports, not a validated full ARDS diagnosis system. Restricted MIMIC data are not distributed.
Stata Codex Skills
No clinical data.
SOFA Respiratory Score Simulation
Simulation data only.
Teaching resources
AI-Based Simulated Patient Encounters for Clinical Reasoning: A Needs Assessment
Creating a COVID-19 Action Plan for GME Programs
Enhancing Medical Student Quality Improvement Education through Immersion
B38-12 Intern Code Blue and Rapid Response Leadership: A Pre-post Evaluation of a Micro-Module Curriculum
doi:10.1093/ajrccm/aamag162.939 Repository: Inpatient Emergency Leadership Seminar Analysis
C56-19 Beyond Verification: Exploring Resident Attitudes and Behaviors in Code-Status Discussions
Enhancing intern leadership of inpatient emergencies
PAP, RADs, HMVs: Historical pathways and the current landscape
A working text companion for pulmonary and critical care fellows covering PAP, respiratory assist devices, and home mechanical ventilators.
Diagnostic Reasoning Notebooks
Synthetic teaching examples and animation source only; no patient data. Final narrated movies are not public.
Code Blue and Rapid Response Leadership
Educational materials only.
PCCM Fellows Statistics Workshop
Teaching materials only.
Introduction to Clinical Research
Teaching materials only.
For the complete machine-readable catalog, see all public research repositories.