Draft

70  Anaphylaxis And Angioedema

70.1 What this covers

  • Angioedema
  • Drugs
  • Management

70.2 Learning objectives

  • Angioedema
  • Drugs
  • Management
  • Anaphylaxis

70.3 Bottom line / summary

  • #Anaphylaxis and Angioedema
  • Dermal, SQ, mucosal swelling - non pitting.
  • vasodilation and increased vascular permeability.
  • https://www.sciencedirect.com/science/article/pii/S1323893015302550?via%3Dihub
  • ~50 % associated with urticartia

70.4 Approach

  1. idiopathic
  2. associated with allergic and non-allergic reactions due to antigens (e.g. venom, drugs, foods, pathogens, animals, latex(
  3. C1-INH deficiency: inherited or acquired
  4. ACEi: never associated with urticaria
  5. NSAID: non allergic

70.5 Red flags / when to escalate

  • TODO: List red flags that require urgent escalation.

70.6 Common pitfalls

  • TODO: Capture common errors or missed steps.

70.7 References

  • https://photos.collectednotes.com/photos/5187/06657f72-c3be-4130-92cb-80b80b2a67d5
  • https://photos.collectednotes.com/photos/5187/571cbeb7-2efd-4a67-9fcc-56d8c7230ba0
  • https://www.sciencedirect.com/science/article/pii/S1323893015302550?via%3Dihub
  • https://photos.collectednotes.com/photos/5187/289b7162-b87f-4d79-a3e4-a50195069876
  • https://photos.collectednotes.com/photos/5187/66fdd152-802d-4008-a594-4bc42a33ab34
  • https://photos.collectednotes.com/photos/5187/44e19f57-acc7-4a53-9b73-f5f64ee961b2
  • https://photos.collectednotes.com/photos/5187/f76275de-2577-48e0-bfa5-183952d7f84e
  • https://photos.collectednotes.com/photos/5187/ef6e62b0-dc13-4866-abed-8284d39d790d
  • https://photos.collectednotes.com/photos/5187/67450424-d1fc-4308-8602-87f1b54ea638
  • https://photos.collectednotes.com/photos/5187/67450424-d1fc-4308-8602-87f1b54ea638)#

70.8 Source notes

70.8.1 Anaphylaxis And Angioedema

71 Anaphylaxis and Angioedema

71.1 Angioedema

alt

Dermal, SQ, mucosal swelling - non pitting. vasodilation and increased vascular permeability.

24-72 hour course

  • idiopathic
  • associated with allergic and non-allergic reactions due to antigens (e.g. venom, drugs, foods, pathogens, animals, latex(
  • C1-INH deficiency: inherited or acquired

alt

71.1.0.1 Drugs

https://www.sciencedirect.com/science/article/pii/S1323893015302550?via%3Dihub

alt

~50 % associated with urticartia

  • ACEi: never associated with urticaria

  • NSAID: non allergic alt

  • Antibiotics (particularly beta-lactam)

71.1.1 Management

alt

71.2 Anaphylaxis

alt

alt

alt# Angioedema and Anaphylaxis

71.3 Source materials